MCP-1 modulates chemotaxis by follicular lymphoma cells

Amé-Thomas et al. Intratumoral TFH in follicular lymphoma 1 Characterization of intratumoral follicular helper T cells in follicular lymphoma: role in the survival of malignant B cells

1 INSERM, UMR 917, Rennes, F-35043, France 2 Université Rennes 1, UMR 917, Rennes, F-35043, France 3 Etablissement Français du Sang Bretagne, UMR 917, Rennes, F-35043, France 4 Centre Hospitalier Universitaire (CHU) Rennes, F-35033, France 5 INSERM, U844, Hôpital Saint-Eloi, Montpellier, F-34091, France 6 INSERM, U955, Université Paris 12, Créteil, F-94010, France 7 Hôpital Henri Mondor, Départ...

Thrombolysis of deep vein thrombosis and inhibiting chemotaxis of macrophage by MCP-1 blockage.

OBJECTIVE Deep vein thrombosis (DVT) is one common vascular complication after trauma or surgery. Macrophage plays an important role in recanalization of thrombosis and monocyte chemotactic protein 1 (MCP-1) has a potent chemotactic role for macrophage. This study investigated the role of MCP-1 and macrophage in DVT thrombolysis. MATERIALS AND METHODS DVT mice model was established for evalua...

Reed-Sternberg-like cells in follicular lymphoma

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 32-year-old woman presented with abdominal bloating and postprandial discomfort for 3 weeks. Multiple neck and axillary lymph nodes were palpable on physical examination. The lymph nodes were involved by low grade follicular lymphoma with effacement by clo...

Phosphate modulates receptor sulfotyrosine recognition by the chemokine monocyte chemoattractant protein-1 (MCP-1/CCL2).

Tyrosine sulfation is a widespread post-translational modification that mediates the interactions of secreted and membrane-associated proteins in such varied biological processes as peptide hormone action, adhesion, blood coagulation, complement activation and regulation of leukocyte trafficking. Due to the heterogeneous nature of tyrosine sulfation, detailed biochemical and biophysical studies...

Origin and migration of follicular lymphoma cells.